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Reading genomic signal at whatever resolution the question needs.

Precision diagnostics work happens at two altitudes. One is a person wondering whether their family history is worth a conversation. The other is a partner deciding which variant biology is worth funding. Both start with the same discipline — interpret the signal correctly before anyone acts on it.

Neither portal below provides a diagnosis. Each is designed to get the right person to the right next conversation.

For patients and clients

Intake & early signal portal

A short history checklist and an optional genetic result lookup — built against published hereditary-risk referral criteria, not a proprietary score. The output is a plain-language flag: does this pattern typically warrant a genetic counseling conversation.

  • Personal & family history intake
  • Optional variant lookup
  • Informational only — no diagnosis, no risk percentage
  • Routes to genetic counseling and, where relevant, OpenOnco for confirmatory test comparison
Start the intake →

For biopharma & diagnostics partners

Computational pre-screen (JAK) in progress

Four-gate precision immunotherapy gating

Causal, functional variant stratification across exhaustion & persistence, TME & stress, antigen & escape, and safety & manufacturing — applied to specific franchises, not a generic biomarker pitch.

  • Gate A–D framework, applied per therapeutic modality
  • Live computational pre-screen, starting with JAK1/2 pathway variants
  • Trial architecture & commercial value modeling per use case
View the framework →

Why OpenOnco, not our own test database

OpenOnco is a free, open, vendor-neutral comparison of 100+ liquid biopsy tests across MRD, early detection, and comprehensive genomic profiling. Once someone's history warrants a conversation, comparing which confirmatory test fits is exactly the problem OpenOnco already solves well. We link to it rather than rebuild it.

What this portal doesn't do

It doesn't diagnose, score risk numerically, or replace a clinician. It flags patterns against published referral criteria and points toward a genetic counselor. Anyone with a personal health concern should talk to a healthcare provider regardless of what the intake returns.